January 12, 2010

Comparative Genetic Maps visualisation: CMap3D

Filed under: Bioinformatics,Computational Biology — Biointelligence: Education,Training & Consultancy Services @ 5:52 am
Tags: , , , ,

Chromosome mapping by counting the number of recombinants produces a genetic map of the chromosome. But all the genes on the chromosome are incorporated in a single molecule of DNA. Genes are simply portions of the molecule (open reading frames or ORFs) encoding products that create the observed trait (phenotype). The rapid progress in DNA sequencing has produced complete genomes for hundreds of microbes and several eukaryotes.

Genetic linkage mapping enables the study of genome organisation and the association of heritable traits with regions of sequenced genomes and underlying genome sequence variation. Comparative genetic mapping is particularly powerful as it allows a translation of information between related genomes and gives an insight into genome evolution.

CMap3D isĀ  powerful tool to graphically compare multiple genetic maps in three-dimensional space.CMap3D is a stand-alone application and is available for Windows, OS X, and Linux. This software is free for academic users.

For more information refer this link: