October 13, 2009

QuickGo: A browser for Gene Ontology

Filed under: Bioinformatics,Computational Biology,Systems Biology — Biointelligence: Education,Training & Consultancy Services @ 12:44 pm
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The Gene Ontology project is a major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases. The aims of the Gene Ontology project are threefold:
1. Firstly, to maintain and further develop its controlled vocabulary of gene and gene product attributes.
2. Secondly, to annotate genes and gene products, and assimilate and disseminate annotation data.
3. Thirdly, to provide tools to facilitate access to all aspects of the data provided by the Gene Ontology project.

QuickGO is a web-based tool which allows easy browsing of the
Gene Ontology and all associated GO annotations provided by the
GOA group. It provides a comprehensive set of both electronic and
manual annotations from a large number of curation groups.QuickGO users can view and search information provided for GO terms (identifiers, words/phrases in the title or definition, cross-references and synonyms), as well as protein data from Uni- ProtKB (accession numbers, names and gene symbols). Results are ranked so that terms most closely matching the query are returned first. Individual words and combinations of words are scored according to the field in which they occur and their frequency within GO.

QuickGO is updated weekly with protein names, gene symbols, accessions and taxonomy data from UniProtKB. Single or multiple protein accessions can be queried and selected proteins will display all associated GO annotations, both electronic and manual.

QuickGo can be accessed from the EBI website. Here is the link: